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PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells
BACKGROUND: Combination therapy is key to improving cancer treatment efficacy. Phorbol 12-myristate 13-acetate (PMA), a well-known PKC activator, increases the cytotoxicity of several anticancer drugs. Apicularen A induces cytotoxicity in tumor cells through disrupting microtubule networks by tubuli...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901760/ https://ncbi.nlm.nih.gov/pubmed/24447339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-36 |
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