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Emerging Roles of the Nucleolus in Regulating the DNA Damage Response: The Noncanonical DNA Repair Enzyme APE1/Ref-1 as a Paradigmatical Example

Significance: An emerging concept in DNA repair mechanisms is the evidence that some key enzymes, besides their role in the maintenance of genome stability, display also unexpected noncanonical functions associated with RNA metabolism in specific subcellular districts (e.g., nucleoli). During the ev...

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Detalhes bibliográficos
Main Authors: Antoniali, Giulia, Lirussi, Lisa, Poletto, Mattia, Tell, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901381/
https://ncbi.nlm.nih.gov/pubmed/23879289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5491
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