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SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements
Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional protein contributing to genome stability via repair of DNA lesions via the base excision repair pathway. It also plays a role in gene expression regulation and RNA metabolism. Another, poorly characterized function is its ability to bi...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3923644/ https://ncbi.nlm.nih.gov/pubmed/24356447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-05-0286 |
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