Chemical Synthesis of U1 snRNA Derivatives

[Image: see text] U1 snRNA is an interesting biological tool for splicing correction and regulation of gene expression. However, U1 snRNA has never been chemically synthesized. In this study, the first chemical synthesis of U1snRNA and its analogues was carried out. Moreover, it was found that the b...

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Main Authors: Ohkubo, Akihiro, Kondo, Yasushi, Suzuki, Makoto, Kobayashi, Haruki, Kanamori, Takashi, Masaki, Yoshiaki, Seio, Kohji, Nagai, Kiyoshi, Sekine, Mitsuo
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2013
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901379/
https://ncbi.nlm.nih.gov/pubmed/23952175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401917r
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