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Assays for determining heparan sulfate and heparin O-sulfotransferase activity and specificity

O-sulfotransferases (OSTs) are critical enzymes in the cellular biosynthesis of the biologically and pharmacologically important heparan sulfate and heparin. Recently, these enzymes have been cloned and expressed in bacteria for application in the chemoenzymatic synthesis of glycosaminoglycan-based...

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Autori principali: Sterner, Eric, Li, Lingyun, Paul, Priscilla, Beaudet, Julie M., Liu, Jian, Linhardt, Robert J., Dordick, Jonathan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901155/
https://ncbi.nlm.nih.gov/pubmed/24271188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-013-7470-4
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