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Functionalized liposomes loaded with siRNAs targeting ion channels in effector memory T cells as a potential therapy for autoimmunity
Effector memory T cells (T(M)) play a key role in the pathology of certain autoimmune disorders. The activity of effector T(M) cells is under the control of Kv1.3 ion channels, which facilitate the Ca(2+) influx necessary for T cell activation and function, i.e. cytokine release and proliferation. C...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900865/ https://ncbi.nlm.nih.gov/pubmed/24075407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.09.019 |
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