Mechanisms of the Scaffold Subunit in Facilitating Protein Phosphatase 2A Methylation

The function of the biologically essential protein phosphatase 2A (PP2A) relies on formation of diverse heterotrimeric holoenzymes, which involves stable association between PP2A scaffold (A) and catalytic (C or PP2Ac) subunits and binding of variable regulatory subunits. Holoenzyme assembly is high...

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Bibliographic Details
Main Authors: Stanevich, Vitali, Zheng, Aiping, Guo, Feng, Jiang, Li, Wlodarchak, Nathan, Xing, Yongna
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900686/
https://ncbi.nlm.nih.gov/pubmed/24466300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086955
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