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Mechanisms of the Scaffold Subunit in Facilitating Protein Phosphatase 2A Methylation

The function of the biologically essential protein phosphatase 2A (PP2A) relies on formation of diverse heterotrimeric holoenzymes, which involves stable association between PP2A scaffold (A) and catalytic (C or PP2Ac) subunits and binding of variable regulatory subunits. Holoenzyme assembly is high...

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Hlavní autoři: Stanevich, Vitali, Zheng, Aiping, Guo, Feng, Jiang, Li, Wlodarchak, Nathan, Xing, Yongna
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900686/
https://ncbi.nlm.nih.gov/pubmed/24466300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086955
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