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miR-122 Targets Pyruvate Kinase M2 and Affects Metabolism of Hepatocellular Carcinoma
In contrast to normal differentiated cells that depend on mitochondrial oxidative phosphorylation for energy production, cancer cells have evolved to utilize aerobic glycolysis (Warburg’s effect), with benefit of providing intermediates for biomass production. MicroRNA-122 (miR-122) is highly expres...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3900676/ https://ncbi.nlm.nih.gov/pubmed/24466275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086872 |
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