miR-122 Targets Pyruvate Kinase M2 and Affects Metabolism of Hepatocellular Carcinoma

In contrast to normal differentiated cells that depend on mitochondrial oxidative phosphorylation for energy production, cancer cells have evolved to utilize aerobic glycolysis (Warburg’s effect), with benefit of providing intermediates for biomass production. MicroRNA-122 (miR-122) is highly expres...

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Detalhes bibliográficos
Main Authors: Liu, Angela M., Xu, Zhi, Shek, Felix H., Wong, Kwong-Fai, Lee, Nikki P., Poon, Ronnie T., Chen, Jinfei, Luk, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900676/
https://ncbi.nlm.nih.gov/pubmed/24466275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086872
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