miR-122 Targets Pyruvate Kinase M2 and Affects Metabolism of Hepatocellular Carcinoma

In contrast to normal differentiated cells that depend on mitochondrial oxidative phosphorylation for energy production, cancer cells have evolved to utilize aerobic glycolysis (Warburg’s effect), with benefit of providing intermediates for biomass production. MicroRNA-122 (miR-122) is highly expres...

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Dades bibliogràfiques
Autors principals: Liu, Angela M., Xu, Zhi, Shek, Felix H., Wong, Kwong-Fai, Lee, Nikki P., Poon, Ronnie T., Chen, Jinfei, Luk, John M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900676/
https://ncbi.nlm.nih.gov/pubmed/24466275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086872
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