Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study

OBJECTIVE: Serum α-fetoprotein (AFP) is the most commonly used biomarker for screening hepatocellular carcinoma (HCC) but fails to detect about half of the patients. Thus, we investigated if circulating microRNAs (miRNAs) could outperform AFP for HCC detection. DESIGN: A retrospective cohort study....

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Autors principals: Liu, Angela M, Yao, Tzy-Jyun, Wang, Wei, Wong, Kwong-Fai, Lee, Nikki P, Fan, Sheung Tat, Poon, Ronnie T P, Gao, Chunfang, Luk, John M
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2012
Matèries:
Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308260/
https://ncbi.nlm.nih.gov/pubmed/22403344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2012-000825
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