miR-122 Targets Pyruvate Kinase M2 and Affects Metabolism of Hepatocellular Carcinoma

In contrast to normal differentiated cells that depend on mitochondrial oxidative phosphorylation for energy production, cancer cells have evolved to utilize aerobic glycolysis (Warburg’s effect), with benefit of providing intermediates for biomass production. MicroRNA-122 (miR-122) is highly expres...

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Autores principales: Liu, Angela M., Xu, Zhi, Shek, Felix H., Wong, Kwong-Fai, Lee, Nikki P., Poon, Ronnie T., Chen, Jinfei, Luk, John M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900676/
https://ncbi.nlm.nih.gov/pubmed/24466275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086872
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