G(0)-G(1) Transition and the Restriction Point in Pancreatic β-Cells In Vivo

Most of our knowledge on cell kinetics stems from in vitro studies of continuously dividing cells. In this study, we determine in vivo cell-cycle parameters of pancreatic β-cells, a largely quiescent population, using drugs that mimic or prevent glucose-induced replication of β-cells in mice. Quiesc...

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Autores principales: Hija, Ayat, Salpeter, Seth, Klochendler, Agnes, Grimsby, Joseph, Brandeis, Michael, Glaser, Benjamin, Dor, Yuval
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2014
Materias:
Islet Studies
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900543/
https://ncbi.nlm.nih.gov/pubmed/24130333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1035
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