Glucose Regulates Cyclin D2 Expression in Quiescent and Replicating Pancreatic β-Cells Through Glycolysis and Calcium Channels

Understanding the molecular triggers of pancreatic β-cell proliferation may facilitate the development of regenerative therapies for diabetes. Genetic studies have demonstrated an important role for cyclin D2 in β-cell proliferation and mass homeostasis, but its specific function in β-cell division...

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Detalhes bibliográficos
Main Authors: Salpeter, Seth J., Klochendler, Agnes, Weinberg-Corem, Noa, Porat, Shay, Granot, Zvi, Shapiro, A. M. James, Magnuson, Mark A., Eden, Amir, Grimsby, Joseph, Glaser, Benjamin, Dor, Yuval
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Diabetes-Insulin-Glucagon-Gastrointestinal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115606/
https://ncbi.nlm.nih.gov/pubmed/21521747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1372
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