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Glucose and aging control the quiescence period that follows pancreatic beta cell replication

Pancreatic beta cell proliferation has emerged as the principal mechanism for homeostatic maintenance of beta cell mass during adult life. This underscores the importance of understanding the mechanisms of beta cell replication and suggests novel approaches for regenerative therapy to treat diabetes...

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Main Authors: Salpeter, Seth J., Klein, Allon M., Huangfu, Danwei, Grimsby, Joseph, Dor, Yuval
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934733/
https://ncbi.nlm.nih.gov/pubmed/20823063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.054304
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