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Steady-state theory of the interference of GTP hydrolysis in the mechanism of microtubule assembly.

A model is presented for the interference of GTP hydrolysis in the mechanism of microtubule assembly. This model is suggested by previous results showing that both GTP and GDP are present at microtubule ends because of GTP hydrolysis and that tubulin does not bind to a GDP-bound end. The analytical...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hill, T L, Carlier, M F
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390029/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6580643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.23.7234
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