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Steady-state theory of the interference of GTP hydrolysis in the mechanism of microtubule assembly.

A model is presented for the interference of GTP hydrolysis in the mechanism of microtubule assembly. This model is suggested by previous results showing that both GTP and GDP are present at microtubule ends because of GTP hydrolysis and that tubulin does not bind to a GDP-bound end. The analytical...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hill, T L, Carlier, M F
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390029/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6580643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.23.7234
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