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Non-Uniform Membrane Diffusion Enables Steady-State Cell Polarization via Vesicular Trafficking

Actin-based vesicular trafficking of Cdc42, leading to a polarized concentration of the GTPase, has been implicated in cell polarization, but it was recently debated whether this mechanism allows stable maintenance of cell polarity. Here we show that endocytosis and exocytosis are spatially segregat...

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Detalhes bibliográficos
Main Authors: Slaughter, Brian D., Unruh, Jay R., Das, Arupratan, Smith, Sarah E., Rubinstein, Boris, Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900288/
https://ncbi.nlm.nih.gov/pubmed/23340420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2370
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