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Non-Uniform Membrane Diffusion Enables Steady-State Cell Polarization via Vesicular Trafficking

Actin-based vesicular trafficking of Cdc42, leading to a polarized concentration of the GTPase, has been implicated in cell polarization, but it was recently debated whether this mechanism allows stable maintenance of cell polarity. Here we show that endocytosis and exocytosis are spatially segregat...

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Библиографические подробности
Главные авторы: Slaughter, Brian D., Unruh, Jay R., Das, Arupratan, Smith, Sarah E., Rubinstein, Boris, Li, Rong
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900288/
https://ncbi.nlm.nih.gov/pubmed/23340420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2370
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