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IMPUTATION-BASED ASSESSMENT OF NEXT GENERATION RARE EXOME VARIANT ARRAYS

A striking finding from recent large-scale sequencing efforts is that the vast majority of variants in the human genome are rare and found within single populations or lineages. These observations hold important implications for the design of the next round of disease variant discovery efforts—if ge...

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Detalhes bibliográficos
Main Authors: MARTIN, ALICIA R., TSE, GERARD, BUSTAMANTE, CARLOS D., KENNY, EIMEAR E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900244/
https://ncbi.nlm.nih.gov/pubmed/24297551
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