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3-Hydroxy-3-methylglutaryl-CoA reductase: a transmembrane glycoprotein of the endoplasmic reticulum with N-linked "high-mannose" oligosaccharides.

3-Hydroxy-3-methylglutaryl-CoA reductase (EC 1.1.1.34) is an abundant protein of the crystalloid endoplasmic reticulum of UT-1 cells, a line of cultured hamster cells that over-produces the reductase as a result of gene amplification. In the current studies, we show that reductase in UT-1 cells is a...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Liscum, L, Cummings, R D, Anderson, R G, DeMartino, G N, Goldstein, J L, Brown, M S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6580634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.23.7165
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