MeCP2: a novel Huntingtin interactor

Transcriptional dysregulation has been proposed to play a major role in the pathology of Huntington's disease (HD). However, the mechanisms that cause selective downregulation of target genes remain unknown. Previous studies have shown that mutant huntingtin (Htt) protein interacts with a numbe...

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Autores principales: McFarland, Karen N., Huizenga, Megan N., Darnell, Shayna B., Sangrey, Gavin R., Berezovska, Oksana, Cha, Jang-Ho J., Outeiro, Tiago F., Sadri-Vakili, Ghazaleh
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900110/
https://ncbi.nlm.nih.gov/pubmed/24105466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt499
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