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Mammalian 5′-capped microRNA precursors that generate a single microRNA

MicroRNAs (miRNAs) are short RNA gene regulators typically produced from primary transcripts that are cleaved by the nuclear Microprocessor complex, with the resulting precursor miRNA hairpins exported by Exportin-5 and processed by cytoplasmic Dicer to yield two (5p- and 3p-) miRNAs. Here, we docum...

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Détails bibliographiques
Auteurs principaux: Xie, Mingyi, Li, Mingfeng, Vilborg, Anna, Lee, Nara, Shu, Mei-Di, Yartseva, Valeria, Šestan, Nenad, Steitz, Joan A.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899828/
https://ncbi.nlm.nih.gov/pubmed/24360278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.027
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