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Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production
MicroRNAs (miRNAs) are noncoding RNAs with important roles in regulating gene expression. In studying the earliest nuclear steps of miRNA biogenesis, we observe that primary miRNA (pri-miRNA) transcripts retained at transcription sites due to the deletion of 3′-end processing signals are converted m...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447899/ https://ncbi.nlm.nih.gov/pubmed/18625843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200803111 |
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