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Mammalian 5′-capped microRNA precursors that generate a single microRNA

MicroRNAs (miRNAs) are short RNA gene regulators typically produced from primary transcripts that are cleaved by the nuclear Microprocessor complex, with the resulting precursor miRNA hairpins exported by Exportin-5 and processed by cytoplasmic Dicer to yield two (5p- and 3p-) miRNAs. Here, we docum...

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Detalhes bibliográficos
Main Authors: Xie, Mingyi, Li, Mingfeng, Vilborg, Anna, Lee, Nara, Shu, Mei-Di, Yartseva, Valeria, Šestan, Nenad, Steitz, Joan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899828/
https://ncbi.nlm.nih.gov/pubmed/24360278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.027
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