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Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering
Ammonia is a ubiquitous waste product of protein metabolism that can accumulate in numerous metabolic disorders, causing neurological dysfunction ranging from cognitive impairment to tremor, ataxia, seizures, coma and death(1). The brain is especially vulnerable to ammonia as it readily crosses the...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899396/ https://ncbi.nlm.nih.gov/pubmed/24240184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3400 |
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