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General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex

Calcium signaling represents the principle pathway by which astrocytes respond to neuronal activity. General anesthetics are routinely used in clinical practice to induce a sleep-like state, allowing otherwise painful procedures to be performed. Anesthetic drugs are thought to mainly target neurons...

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Detalhes bibliográficos
Main Authors: Thrane, Alexander Stanley, Thrane, Vinita Rangroo, Zeppenfeld, Douglas, Lou, Nanhong, Xu, Qiwu, Nagelhus, Erlend Arnulf, Nedergaard, Maiken
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503159/
https://ncbi.nlm.nih.gov/pubmed/23112168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209448109
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