Genomic Analyses Reveal Broad Impact of miR-137 on Genes Associated with Malignant Transformation and Neuronal Differentiation in Glioblastoma Cells

miR-137 plays critical roles in the nervous system and tumor development; an increase in its expression is required for neuronal differentiation while its reduction is implicated in gliomagenesis. To evaluate the potential of miR-137 in glioblastoma therapy, we conducted genome-wide target mapping i...

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Bibliografiset tiedot
Päätekijät: Tamim, Saleh, Vo, Dat T., Uren, Philip J., Qiao, Mei, Bindewald, Eckart, Kasprzak, Wojciech K., Shapiro, Bruce A., Nakaya, Helder I., Burns, Suzanne C., Araujo, Patricia R., Nakano, Ichiro, Radek, Agnes J., Kuersten, Scott, Smith, Andrew D., Penalva, Luiz O. F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899048/
https://ncbi.nlm.nih.gov/pubmed/24465609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085591
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