Genomic Analyses Reveal Broad Impact of miR-137 on Genes Associated with Malignant Transformation and Neuronal Differentiation in Glioblastoma Cells

miR-137 plays critical roles in the nervous system and tumor development; an increase in its expression is required for neuronal differentiation while its reduction is implicated in gliomagenesis. To evaluate the potential of miR-137 in glioblastoma therapy, we conducted genome-wide target mapping i...

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Detalhes bibliográficos
Main Authors: Tamim, Saleh, Vo, Dat T., Uren, Philip J., Qiao, Mei, Bindewald, Eckart, Kasprzak, Wojciech K., Shapiro, Bruce A., Nakaya, Helder I., Burns, Suzanne C., Araujo, Patricia R., Nakano, Ichiro, Radek, Agnes J., Kuersten, Scott, Smith, Andrew D., Penalva, Luiz O. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899048/
https://ncbi.nlm.nih.gov/pubmed/24465609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085591
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