Genomic Analyses Reveal Broad Impact of miR-137 on Genes Associated with Malignant Transformation and Neuronal Differentiation in Glioblastoma Cells

miR-137 plays critical roles in the nervous system and tumor development; an increase in its expression is required for neuronal differentiation while its reduction is implicated in gliomagenesis. To evaluate the potential of miR-137 in glioblastoma therapy, we conducted genome-wide target mapping i...

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Hlavní autoři: Tamim, Saleh, Vo, Dat T., Uren, Philip J., Qiao, Mei, Bindewald, Eckart, Kasprzak, Wojciech K., Shapiro, Bruce A., Nakaya, Helder I., Burns, Suzanne C., Araujo, Patricia R., Nakano, Ichiro, Radek, Agnes J., Kuersten, Scott, Smith, Andrew D., Penalva, Luiz O. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899048/
https://ncbi.nlm.nih.gov/pubmed/24465609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085591
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