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PrimPol, an Archaic Primase/Polymerase Operating in Human Cells
We describe a second primase in human cells, PrimPol, which has the ability to start DNA chains with deoxynucleotides unlike regular primases, which use exclusively ribonucleotides. Moreover, PrimPol is also a DNA polymerase tailored to bypass the most common oxidative lesions in DNA, such as abasic...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cell Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899013/ https://ncbi.nlm.nih.gov/pubmed/24207056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.09.025 |
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