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Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression()
Mutations of the PTEN-induced kinase 1 (PINK1) gene are a cause of autosomal recessive Parkinson's disease (PD). This gene encodes a mitochondrial serine/threonine kinase, which is partly localized to mitochondria, and has been shown to play a role in protecting neuronal cells from oxidative st...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Academic Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898697/ https://ncbi.nlm.nih.gov/pubmed/24184327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.10.021 |
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