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Conversion of Human Fibroblasts to Functional Endothelial Cells by Defined Factors
OBJECTIVE: Transdifferentiation of fibroblasts to endothelial cells (ECs) may provide a novel therapeutic avenue for diseases including ischemia and fibrosis. Here we demonstrate that human fibroblasts can be transdifferentiated into functional ECs by using only two factors, Oct4 and Klf4, under ind...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898631/ https://ncbi.nlm.nih.gov/pubmed/23520160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301167 |
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