The Modulation of Endothelial Cell Morphology, Function, and Survival Using Anisotropic Nanofibrillar Collagen Scaffolds

Endothelial cells (ECs) are aligned longitudinally under laminar flow, whereas they are polygonal and poorly aligned in regions of disturbed flow. The unaligned ECs in disturbed flow fields manifest altered function and reduced survival that promote lesion formation. We demonstrate that the alignmen...

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Detalhes bibliográficos
Main Authors: Huang, Ngan F., Okogbaa, Janet, Lee, Jerry C., Jha, Arshi, Zaitseva, Tatiana S., Paukshto, Michael V., Sun, John, Punjya, Niraj, Fuller, Gerald G., Cooke, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695739/
https://ncbi.nlm.nih.gov/pubmed/23480958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.02.036
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