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Genetic construction and properties of a diphtheria toxin-related substance P fusion protein: in vitro destruction of cells bearing substance P receptors.

We have genetically replaced the native receptor binding domain of diphtheria toxin with an extended form of substance P (SP): SP-glycine (SP-Gly). The resulting fusion protein, DAB389SP-Gly, is composed of the catalytic and transmembrane domains of diphtheria toxin genetically coupled to SP-Gly. Be...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:Proc Natl Acad Sci U S A
Үндсэн зохиолчид: Fisher, C E, Sutherland, J A, Krause, J E, Murphy, J R, Leeman, S E, vanderSpek, J C
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: National Academy of Sciences 1996
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38986/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692995/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7341
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