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Computational Design of Ligand Binding Proteins with High Affinity and Selectivity
The ability to design proteins with high affinity and selectivity for any given small molecule would have numerous applications in biosensing, diagnostics, and therapeutics, and is a rigorous test of our understanding of the physiochemical principles that govern molecular recognition phenomena. Atte...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898436/ https://ncbi.nlm.nih.gov/pubmed/24005320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12443 |
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