Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives.

So324 is a 2',3'-dideoxy-2',3'-didehydrothymidine-5'-monophosphate (d4T-MP) prodrug containing at the phosphate moiety a phenyl group and the methylester of alanine linked to the phosphate through a phosphoramidate linkage. So324 has anti-HIV activity in human CEM, MT4, and...

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Bibliographische Detailangaben
Hauptverfasser: Balzarini, J, Karlsson, A, Aquaro, S, Perno, C F, Cahard, D, Naesens, L, De Clercq, E, McGuigan, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38977/
https://ncbi.nlm.nih.gov/pubmed/8692986
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