REGULATION OF GLUCOSE HOMEOSTASIS THROUGH XBP1-FOXO1 INTERACTION

To date, our understanding of the role of X-Box Binding Protein 1 (XBP1) in metabolic processes was limited to its ability to up-regulate ER folding capacity and thereby, to increase insulin sensitivity. Here, we demonstrate that XBP1s interacts with Forkhead box O1 (FoxO1) transcription factor and...

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Autors principals: Zhou, Yingjiang, Lee, Justin, Reno, Candace M., Sun, Cheng, Park, Sang Won, Chung, Jason, Lee, Jaemin, Fisher, Simon J., White, Morris F., Biddinger, Sudha B., Ozcan, Umut
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897616/
https://ncbi.nlm.nih.gov/pubmed/21317886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2293
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