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Rapid and Unambiguous Detection of DNase I Hypersensitive Site in Rare Population of Cells
DNase I hypersensitive (DHS) sites are important for understanding cis regulation of gene expression. However, existing methods for detecting DHS sites in small numbers of cells can lead to ambiguous results. Here we describe a simple new method, in which DNA fragments with ends generated by DNase I...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3897510/ https://ncbi.nlm.nih.gov/pubmed/24465674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085740 |
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