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The Role of Flotillins in Regulating Aβ Production, Investigated Using Flotillin 1-/-, Flotillin 2-/- Double Knockout Mice

Flotillin 1 and flotillin 2 associate in the plasma membrane to form microdomains that have roles in cell signaling, regulation of cell-cell contacts, membrane-cytoskeletal interactions, and endocytosis. They are thought to be involved in the trafficking and hence processing of the Amyloid Precursor...

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Detalhes bibliográficos
Main Authors: Bitsikas, Vassilis, Riento, Kirsi, Howe, Jonathan D., Barry, Nicholas P., Nichols, Benjamin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897416/
https://ncbi.nlm.nih.gov/pubmed/24465508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085217
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