Def1 Promotes the Degradation of Pol3 for Polymerase Exchange to Occur During DNA-Damage–Induced Mutagenesis in Saccharomyces cerevisiae

DNA damages hinder the advance of replication forks because of the inability of the replicative polymerases to synthesize across most DNA lesions. Because stalled replication forks are prone to undergo DNA breakage and recombination that can lead to chromosomal rearrangements and cell death, cells p...

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Detaylı Bibliyografya
Asıl Yazarlar: Daraba, Andreea, Gali, Vamsi K., Halmai, Miklós, Haracska, Lajos, Unk, Ildiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897375/
https://ncbi.nlm.nih.gov/pubmed/24465179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001771
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