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Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats

Compared to socially housed (SH) rats, adult isolation-reared (IR) rats exhibit phenotypes relevant to schizophrenia (SZ), including reduced prepulse inhibition (PPI) of startle. PPI is normally regulated by the medial prefrontal cortex (mPFC) and nucleus accumbens (NAC). We assessed PPI, auditory-e...

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書誌詳細
主要な著者: Swerdlow, Neal R., Light, Gregory A., Trim, Ryan S., Breier, Michelle R., Hines, Samantha R., Powell, Susan B.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897308/
https://ncbi.nlm.nih.gov/pubmed/24076151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2013.09.005
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