Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats

Compared to socially housed (SH) rats, adult isolation-reared (IR) rats exhibit phenotypes relevant to schizophrenia (SZ), including reduced prepulse inhibition (PPI) of startle. PPI is normally regulated by the medial prefrontal cortex (mPFC) and nucleus accumbens (NAC). We assessed PPI, auditory-e...

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Hlavní autoři: Swerdlow, Neal R., Light, Gregory A., Trim, Ryan S., Breier, Michelle R., Hines, Samantha R., Powell, Susan B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897308/
https://ncbi.nlm.nih.gov/pubmed/24076151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2013.09.005
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