Coupling of gene expression in medial prefrontal cortex and nucleus accumbens after neonatal ventral hippocampal lesions accompanies deficits in sensorimotor gating and auditory processing in rats

BACKGROUND: After neonatal ventral hippocampal lesions (NVHLs), adult rats exhibit evidence of neural processing deficits relevant to schizophrenia, including reduced prepulse inhibition (PPI) of acoustic startle and impaired sensory processing. In intact rats, the regulation of PPI by the ventral h...

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Hauptverfasser: Swerdlow, Neal R., Powell, Susan B., Breier, Michelle R., Hines, Samantha R., Light, Gregory A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825835/
https://ncbi.nlm.nih.gov/pubmed/23810830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.06.003
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