ANTI-INFLAMMATORY PROPERTIES OF PROSTAGLANDIN E2: DELETION OF MICROSOMAL PROSTAGLANDIN E SYNTHASE-1 EXACERBATES NON-IMMUNE INFLAMMATORY ARTHRITIS IN MICE

Prostanoids and PGE2 in particular have been long viewed as one of the major mediators of inflammation in arthritis. However, experimental data indicate that PGE2 can serve both pro- and anti-inflammatory functions. We have previously shown (Kojima, F. et al. 2008 J. Immunol. 180, 8361-8368) that mi...

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Autores principales: Frolov, Andrey, Yang, Lihua, Dong, Hua, Hammock, Bruce D., Crofford, Leslie J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897272/
https://ncbi.nlm.nih.gov/pubmed/24055573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2013.08.003
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