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Extracellular signal-regulated kinases1/2 signaling pathways are not involved in endothelin regulation of mouse inner medullary collecting duct nitric oxide production

AIMS: To determine if endothelin-1 (ET-1) stimulates the phosphorylation of ERK1/2 in the mouse inner medullary collecting duct (IMCD), and if this in turn upregulates nitric oxide (NO) production. MAIN METHODS: Confluent mouse IMCD segment-3 cells (mIMCD-3) were stimulated with 50 nM ET-1 for 24 hr...

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Hlavní autoři: Hyndman, Kelly A, MacDonell, Alexander H., Pollock, Jennifer S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897254/
https://ncbi.nlm.nih.gov/pubmed/23293787
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