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A two dimensional ERK-AKT signaling code for an NGF-triggered cell fate decision

Growth factors activate Ras, PI3K and other signaling pathways. It is not well understood how these signals are translated by individual cells into a decision to proliferate or differentiate. Here, using single-cell image analysis of nerve growth factor (NGF)-stimulated PC12 cells, we identified a t...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Jia-Yun, Lin, Jia-Ren, Cimprich, Karlene A., Meyer, Tobias
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897208/
https://ncbi.nlm.nih.gov/pubmed/22206868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.023
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