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A two dimensional ERK-AKT signaling code for an NGF-triggered cell fate decision
Growth factors activate Ras, PI3K and other signaling pathways. It is not well understood how these signals are translated by individual cells into a decision to proliferate or differentiate. Here, using single-cell image analysis of nerve growth factor (NGF)-stimulated PC12 cells, we identified a t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3897208/ https://ncbi.nlm.nih.gov/pubmed/22206868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.023 |
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