Cell Fate Decision as High-Dimensional Critical State Transition

Cell fate choice and commitment of multipotent progenitor cells to a differentiated lineage requires broad changes of their gene expression profile. But how progenitor cells overcome the stability of their gene expression configuration (attractor) to exit the attractor in one direction remains elusi...

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Bibliografiska uppgifter
I publikationen:PLoS Biol
Huvudupphovsmän: Mojtahedi, Mitra, Skupin, Alexander, Zhou, Joseph, Castaño, Ivan G., Leong-Quong, Rebecca Y. Y., Chang, Hannah, Trachana, Kalliopi, Giuliani, Alessandro, Huang, Sui
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189937/
https://ncbi.nlm.nih.gov/pubmed/28027308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2000640
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