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Cell Fate Decision as High-Dimensional Critical State Transition

Cell fate choice and commitment of multipotent progenitor cells to a differentiated lineage requires broad changes of their gene expression profile. But how progenitor cells overcome the stability of their gene expression configuration (attractor) to exit the attractor in one direction remains elusi...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Mojtahedi, Mitra, Skupin, Alexander, Zhou, Joseph, Castaño, Ivan G., Leong-Quong, Rebecca Y. Y., Chang, Hannah, Trachana, Kalliopi, Giuliani, Alessandro, Huang, Sui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189937/
https://ncbi.nlm.nih.gov/pubmed/28027308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2000640
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