Deficient Leptin Signaling Ameliorates Systemic Lupus Erythematosus Lesions in MRL/Mp-Fas(lpr) Mice

Leptin is secreted by adipocytes, the placenta, and the stomach. It not only controls appetite through leptin receptors in the hypothalamus, it also regulates immunity. In the current study, we produced leptin-deficient MRL/Mp-Fas(lpr) mice to investigate the potential role of leptin in autoimmunity...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Fujita, Yoshimasa, Fujii, Takao, Mimori, Tsuneyo, Sato, Tomomi, Nakamura, Takuji, Iwao, Haruka, Nakajima, Akio, Miki, Miyuki, Sakai, Tomoyuki, Kawanami, Takafumi, Tanaka, Masao, Masaki, Yasufumi, Fukushima, Toshihiro, Okazaki, Toshiro, Umehara, Hisanori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: AAI 2014
Onderwerpen:
Clinical and Human Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897175/
https://ncbi.nlm.nih.gov/pubmed/24391210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301685
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items