Self-Reactivity and the Expression of Memory Markers Vary Independently in MRL-Mp+/+ and MRL-Mp-lpr/lpr Mice

MRL-Mp-lpr/lpr mice contain phenotypically abnormal populations of T cells, and exhibit an SLE-like autoimmune disease in which autoantibodies are a prominent feature. We analyzed the phenotype and T-cell receptor Vß expression pattern in CD4(+) T cells of this mutant mouse strain to detect abnormal...

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Библиографические подробности
Главные авторы: Smyth, Lesley, Howell, Michelle, Crispe, I. Nicholas
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 1992
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275871/
https://ncbi.nlm.nih.gov/pubmed/1343099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1992/89109
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